Batman must face his most ruthless nemesis when a deformed madman calling himself "The Joker" seizes control of Gotham's criminal underworld.

An American master chemist plans to score big on a once in a lifetime drug deal. All does not go as planned and he is soon entangled in a web of deceit.

After experimenting on himself and becoming invisible, scientist Jack Griffin, now aggressive due to the drug's effects, seeks a way to reverse the experiment at any cost.